Technetium-99m sulfur colloid

Approved Use: 

• In adults, to assist in the:
  • localization of lymph nodes draining a primary tumor in patients with breast cancer or malignant melanoma when used with a hand-held gamma counter
  • evaluation of peritoneo-venous (LeVeen) shunt patency 
• In adults and pediatric patients, for imaging:
  • areas of functioning reticuloendothelial cells in the liver, spleen and bone marrow 
  • studies of esophageal transit and, gastroesophageal reflux, and detection of pulmonary aspiration of gastric contents

Dose: 

• Breast cancer or malignant melanoma setting (ADULTS): 0.1 - 1 mCi SQ
• LeVeen shunt evaluation (ADULTS): 1 - 3 mCi intraperitoneal injection, or 0.3 - 1 mCi percutaneous transtubal injection
• Liver/spleen imaging (ADULTS): 1 - 8 mCi IV
• ​Liver/spleen imaging (PEDIATRIC): 0.015 - 0.075 mCi/kg IV
• Liver/spleen imaging (NEWBORNS): 0.20 - 0.50 mCI IV
• Bone marrow imaging (ADULTS): 3 - 12 mCi IV
• Bone marrow imaging (PEDIATRIC): 0.03 - 0.15 mCi/kg IV
• Gastroesophageal studies (ADULTS): 0.15 - 0.30 mCi PO
• Gastroesophageal studies (PEDIATRIC): 0.10 - 0.30 mCi PO or nasogastric tube
• Pulmonary aspiration studies (ADULTS): 0.30 - 0.50 mCi PO
• Pulmonary aspiration studies (PEDIATRIC): 0.10 - 0.30 mCi PO or nasogastric tube​

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Manufacturer: Sun Radiopharma
Package Insert
How Supplied: 5 kits per box
Each kit consists of three components:

1. ​Reaction Vial, containing, in lyophilized form, 2 mg sodium thiosulfate anhydrous, 2.3 mg edetate disodium and 18.1 mg bovine gelatin
2. Solution A Vial, containing 1.8 mL 0.148 N hydrochloric acid solution
3. Solution B Vial, containing 1.8 mL aqueous solution of 24.6 mg/mL sodium biphosphate anhydrous and 7.9 mg/mL sodium hydroxide 

​NDC #: 45567-0030-1
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Allergy Information
Product Website
Lymph Node Localization Summary Slides

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Manufacturer: Jubilant Radiopharma
Package Insert
​How Supplied: 5 kits per box
Each kit consists of three components:

1. ​Reaction Vial, containing, in lyophilized form, 2 mg sodium thiosulfate anhydrous, 2.3 mg edetate disodium and 18.1 mg bovine gelatin
2. Solution A Vial, containing 1.8 mL 0.148 N hydrochloric acid solution
3. Solution B Vial, containing 1.8 mL aqueous solution of 24.6 mg/mL sodium biphosphate anhydrous and 7.9 mg/mL sodium hydroxide 

NDC #: 65174-179-01

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Clinical Guidelines:

• ACR-SPR Practice Parameter for the Performance of Gastrointestinal Scintigraphy (2015)
• ACR-SPR Practice Parameter for the Performance of Liver and Spleen Scintigraphy (2015)
• EANM Practice Guidelines for Lymphoscintigraphy and Sentinel Lymph Node Biopsy in Melanoma (2015)
• EANM Practice Guidelines for Lymphoscintigraphy and Sentinel Node Localization in Gynecological Cancers (2014)
• SNMMI Procedure Standard-EANM Practice Guideline for Lymphoscintigraphy and Sentinel Node Localization in Breast Cancer (2013)
• ​SNMMI Procedure Standard-EANM Practice Guideline for Small-Bowel and Colon Transit 1.0 (2013)
• SNMMI Procedure Standard for Gastric Emptying 3.0 (2009)