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Iodine-123 iobenguane (MIBG)

Approved Use:
  • Detection of primary or metastatic pheochromocytoma or neuroblastoma as an adjunct to other diagnostic tests
  • Scintigraphic assessment of sympathetic innervation of the myocardium by measurement of the heart to mediastinum (H/M) ratio of radioactivity uptake in patients with New York Heart Association (NYHA) class II or class III heart failure and left ventricular ejection fraction (LVEF) ≤ 35%. Among these patients, AdreView may be used to help identify patients with lower one and two year mortality risks, as indicated by an H/M ratio ≥ 1.6 
Dose: 
  • Patients ≥ 16 years of age or < 16 years of age and ≥ 70 kg: administer 10 mCi
  • Patients < 16 years of age and < 70 kg: amount scaled to the adult reference activity based on weight (see chart below)

​Brand Name: AdreView™
Manufacturer: GE Healthcare
Package Insert  
How Supplied: 10 mCi
Volume: 5 mL
Calibration: 
  • Tuesday 12:00 PT
  • Wednesday 12:00 PT
  • Thursday 12:00 PT
Expiration: 36 hours after calibration
Availability: must be ordered ≥ 2 business days in advance for delivery on calibration day
NDC #: 17156-235-01

Clinical Guidelines: 
  • ACR–ACNM–SNMMI–SPR Practice Parameter for the Performance of Neuroendocrine Tumor Scintigraphy (2020)
  • EANM Practice Guideline/SNMMI Procedure Standard for Radionuclide Imaging of Pheochromocytoma and Paraganglioma (2019)
  • ASNC Imaging Guidelines for SPECT Nuclear Cardiology Procedures: Stress, Protocols, and Tracers (2016)
  • ACR-SPR Practice Parameter for the Performance of Tumor Scintigraphy (2015)
  • ​EANM Guidelines for I-123/I-131 MIBG Scintigraphy (2012)
Pediatric Dose Chart:
Weight (kg)
Dose (mCi)
3
1.0
4
1.4
6
1.9
8
2.3
10
2.7
12
3.2
14
3.6
16
4.0
18
4.4
20
4.6
22
5.0
24
5.3
26
5.6
28
5.8
30
6.2
32
6.5
34
6.8
36
7.1
38
7.3
40
7.6
42
7.8
44
8.0
46
8.2
48
8.5
50
8.8
52
9.0
54
9.0
56
9.2
58
9.2
60
9.6
62
9.6
64
9.8
66
9.8
68
9.9
Disclaimer
Created by R.C. Riberich ©2016-2022
  • Home
  • Pharmaceuticals
    • Radiopharmaceuticals >
      • C-14 urea
      • Ga-67 citrate
      • In-111 chloride
      • In-111 oxyquinoline
      • In-111 pentatate
      • In-111 pentetreotide
      • I-123 MIBG
      • I-123 ioflupane
      • I-123 sodium iodide capsules
      • I-125 HSA
      • I-125 iothalamate
      • I-131 HSA
      • I-131 MIBG
      • I-131 sodium iodide diagnostic capsules
      • I-131 sodium iodide therapy
      • Lu-177 dotatate
      • Lu-177 vipivotide tetraxetan
      • Mo-99/Tc-99m Generator
      • Ra-223 dichloride
      • Sr-89 chloride
      • Tc-99m bicisate
      • Tc-99m exametazime
      • Tc-99m MAA
      • Tc-99m mebrofenin
      • Tc-99m medronate
      • Tc-99m mertiatide
      • Tc-99m oxidronate
      • Tc-99m pentetate
      • Tc-99m PYP
      • Tc-99m RBC
      • Tc-99m sestamibi
      • Tc-99m succimer
      • Tc-99m sulfur colloid
      • Tc-99m tetrofosmin
      • Tc-99m tilmanocept
      • Tl-201 chloride
      • Xe-133 gas
      • Y-90 chloride
      • Y-90 ibritumomab tiuxetan
    • PET Radiopharmaceuticals >
      • C-11 choline
      • Cu-64 dotatate
      • F-18 florbetaben
      • F-18 florbetapir
      • F-18 flortaucipir
      • F-18 fluciclovine
      • F-18 fludeoxyglucose
      • F-18 fluorodopa
      • F-18 fluoroestradiol
      • F-18 flutemetamol
      • F-18 piflufolastat
      • F-18 sodium fluoride
      • Ga-68 DOTATATE
      • Ga-68 DOTATOC
      • Ga-68 gozetotide
      • N-13 ammonia
      • Rb-82 chloride
    • Nonradioactive Adjuncts
    • Discontinued
  • Calculations
    • Unit Conversions
    • Radioactive Decay
    • Generator Elution Calcs
    • MAA Particle Calcs
    • Pediatric Dosing
  • Helpful Lists
    • Radionuclides
    • Light Sensitive Products
    • Refrigeration
    • NDC Numbers
  • Links
    • Organizations
    • Manufacturers
    • Nuclear Pharmacies
    • Universities
  • What's New
  • About
  • Contact