Technetium-99m macroaggregated albumin (MAA)

Approved Use:

• Lung imaging agent which may be used as an adjunct in the evaluation of pulmonary perfusion in adults and pediatric patients
• Aid in the evaluation of peritoneovenous (LeVeen) shunt patency 

Dose:

• ​Lung imaging (Adult): 1 - 4 mCi; 200,000 - 700,000 particles (350,000 suggested)
• Lung imaging (pediatric): 25 - 50 µCi/kg (usual dose is 30 µCi/kg); see package insert
• Lung imaging (newborn): 200 - 500 µCi; see package insert
• LeVeen shunt patency: 1 - 3 mCi

MAA Particle Calculator

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Manufacturer: Jubilant Radiopharma
Package Insert
Storage: Refrigerate AFTER reconstitution
How Supplied: 30 vial kit
NDC #: 65174-270-30
​Particle Count:

• 3 - 8 million particles per vial
• Certificate of particle count and "simplified reconstitution recommendations" included with each lot.

Examples of Simplified Reconstitution Recommendations:
3 million per vial
4 million per vial
5 million per vial
6 million per vial
​7 million per vial
8 million per vial

Letter from Manufacturer October 2017 (shelf-life increased)

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Brand Name: Pulmotech™ MAA
Manufacturer: Curium
Package Insert
Storage: Refrigerate AFTER reconstitution
How Supplied: 

• 5 vial kit (NDC: 69945-139-20)
• 30 vial kit (NDC:  69945-139-40)

Particle Count:

• 2 million particles per vial
• 3 million particles per vial
• 4 million particles per vial

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Clinical Guidelines:

• ACR-SPR-STR Practice Parameter for the Performance of Pulmonary Scintigraphy (2018)
• SNMMI Procedure Standard for Lung Scintigraphy 4.0 (2011)
• ​ACR-SNMMI-SPR Practice Guideline for the Performance of Pulmonary Scintigraphy in Adults and Children (2009)